If your observations consist of multiple execution blocks (EBs) for the same target source with the same antenna configuration and spectral setup, combining those executions can help reach your proposed sensitivity. There are two primary methods of imaging multiple EBs in CASA.  (For performance reasons, it is strongly advised that you not attempt imaging multiple SPWs with different rest frequencies in the same run of clean.)

1. On the fly, using the CASA task tclean with individual measurement sets as input visibilities (vis),

e.g., tclean(vis=['EB1.ms', 'EB2.ms', 'EB3.ms', ...], spw='0', ...)

2. Using the task concat to combine calibrated measurement sets, then using clean.

(1) Setting all the spectral windows to be combined in tclean

Since the observing epoch is different for each execution, the topocentric sky frequency also usually differs.  The number of SPWs is thus increased in the concatenated data.  For example, if there are 2 EBs with 4 SPWs in each execution, there will be 8 SPWs after concat. To make an image of the first SPW, you need to set spw='0,4' instead of spw='0'.

 e.g., concat(vis=['EB1.ms', 'EB2.ms'], concatvis='calibrated.ms')

        tclean(vis='calibrated.ms', spw='0,4', ...)

(2) Setting the parameter freqtol in concat 

In the case of continuum or line observations with a much larger velocity resolution than the frequency difference between the EBs, the freqtol parameter of concat can be conveniently used to combine SPWs with a slight difference in frequency.

 e.g., concat(vis=['EB1', 'EB2', 'EB3', ...], concatvis='calibrated.ms', freqtol='1MHz')

        tclean(vis='calibrated.ms', spw='0', ...)

The parameter freqtol should not be used if the frequency difference between EBs is larger than ~1/3 of the velocity resolution for line observations. The regridding is performed in the task tclean to transform channel labels and the visibilities to a spectral reference frame which is appropriate for the science analysis, e.g. from TOPO to LSRK, but the transformation is only accurate for the earliest EB. (The regridding in tclean is performed if you have not done cvel or mstransform before clean, or you use the different parameters in tclean from those in cvel/mstransform.)

You can refer to the article "What are the frequency reference frames in CASA?" for more information about reference frames and ALMA. 

Note that when combining multiple measurement sets obtained with different antenna configurations, or measurement sets reduced with different versions of CASA (earlier than 4.2.2 pipeline, or < CASA 4.3 for manual reduction), it is often necessary to adjust the data weights after using concat. Please see the topic in CASA Guides, Data Weights and Combination.